Amy Schumer Wipes Instagram Slate Clean, Embracing a New Chapter

November 12, 2025

Amy Schumer Wipes Instagram Slate Clean, Embracing a New Chapter

New York, NY - Comedian and actress Amy Schumer is starting fresh. The 44-year-old star has deleted all previous photos from her Instagram account, debuting a new, singular post that showcases her recent weight loss and a renewed sense of self. In a move that has sparked conversation among fans and followers, Schumer captioned her glamorous photo in a red Valentino mini-dress with a simple, yet bold statement: "I'm feeling good and happy. Deleted my old pics for no reason!"

This social media reset comes after a period of significant personal and physical transformation for the "Trainwreck" star, who has been remarkably open about her health and wellness journey.

A Candid Look at Health and Weight Loss

For years, Schumer has been a vocal advocate for body positivity while also sharing the unvarnished truth about her struggles with weight and health. She recently revealed her success with the GLP-1 medication Mounjaro, which she says has been a "great" experience, contributing to fuller hair, better skin, and more energy. This came after a "horrible experience" with Ozempic, which she tried nearly three years ago. Schumer disclosed that while she lost 30 pounds on Ozempic, the side effects, including extreme nausea, left her "bedridden" and unable to play with her son, Gene. "I looked great, but I couldn't lift my head off the pillow. So, what's the point?” she recounted.

Her transparency extends beyond weight loss medications. In 2022, Schumer underwent liposuction, a decision she shared publicly to be "real about it" with her fans.

Navigating Health Diagnoses with Humor and Honesty

A significant factor in Schumer's recent health journey has been her diagnosis with Cushing syndrome. The condition, which occurs when the body has an excess of the hormone cortisol, was identified after fans and even doctors online commented on her "puffy" and rounder face. Schumer has exogenous Cushing syndrome, which was brought on by high-dose steroid injections. She has also been candid about her battle with endometriosis, a painful disorder that led to her having her uterus removed in September 2021.

Throughout these challenges, Schumer has used her platform to advocate for women's health. "The shaming and criticism of our ever-changing bodies is something I have dealt with and witnessed for a long time," she stated in an Instagram video. "I want so much for women to love themselves and be relentless when fighting for their own health in a system that usually doesn't believe them."

A Life in the Spotlight: Career, Family, and Fortune

Schumer's career continues to thrive. She has a long list of film and television credits, including Trainwreck, I Feel Pretty, and the Hulu series Life & Beth. Her latest project is the Netflix movie Kinda Pregnant. Looking ahead, Schumer is set to kick off SeriesFest: Season 11 with "Amy Schumer & Friends" at Red Rocks Amphitheatre in April 2025 and is reportedly filming the third season of Life & Beth.

Her professional success has led to a significant net worth, estimated to be around $45 million.

On the personal front, Schumer has been married to chef and farmer Chris Fischer since 2018. Fischer, who is an author and James Beard Award winner, was diagnosed with autism spectrum disorder, a topic Schumer has spoken about with love and humor. The couple welcomed their son, Gene David Fischer, in May 2019.

A Lasting Impression on Comedy and Culture

From her breakout role in the 2015 film Trainwreck, where she shared a memorable and "awkward" comedic sex scene with John Cena, to her award-winning sketch show Inside Amy Schumer, she has consistently pushed boundaries and challenged conventions. Cena has described Schumer as an "angel" who made him feel comfortable during the filming of their intimate scene.

As Amy Schumer steps into this new, seemingly unburdened chapter, her journey remains a compelling narrative of resilience, honesty, and the power of embracing change, both inside and out.